NAD(P)H quinone oxidoreductase 1 regulates neutrophil elastase-induced mucous cell metaplasia

Mucous cell metaplasia (MCM) and neutrophil-predominant airway inflammation are pathological features of chronic inflammatory airway diseases. A signature feature of MCM is increased expression of a major respiratory tract mucin, MUC5AC. Neutrophil elastase (NE) upregulates MUC5AC in primary airway...

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Autors principals: Meyer, Marisa L., Potts-Kant, Erin N., Ghio, Andrew J., Fischer, Bernard M., Foster, W. Michael, Voynow, Judith A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423858/
https://ncbi.nlm.nih.gov/pubmed/22659878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00084.2012
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