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Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice
Neutrophilic inflammation is associated with chronic airway diseases. It has been observed that human neutrophil elastase (HNE), which is secreted by active neutrophils during inflammation, induces both mucin overproduction and goblet cell metaplasia. Several in vitro studies suggest that tumor necr...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652059/ https://ncbi.nlm.nih.gov/pubmed/23564510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00259.2012 |
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