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Structural Insights for Engineering Binding Proteins Based on Non-Antibody Scaffolds

Engineered binding proteins derived from non-antibody scaffolds constitute an increasingly prominent class of reagents in both research and therapeutic applications. The growing number of crystal structures of these “alternative” scaffold-based binding proteins in complex with their targets illustra...

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Detalhes bibliográficos
Main Authors: Gilbreth, Ryan N., Koide, Shohei
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423532/
https://ncbi.nlm.nih.gov/pubmed/22749196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2012.06.001
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