Carbonylation Induces Heterogeneity in Cardiac Ryanodine Receptor Function in Diabetes Mellitus

Heart failure and arrhythmias occur at 3 to 5 times higher rates among individuals with diabetes mellitus, compared with age-matched, healthy individuals. Studies attribute these defects in part to alterations in the function of cardiac type 2 ryanodine receptors (RyR2s), the principal Ca(2+)-releas...

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Asıl Yazarlar: Shao, Chun Hong, Tian, Chengju, Ouyang, Shouqiang, Moore, Caronda J., Alomar, Fadhel, Nemet, Ina, D'Souza, Alicia, Nagai, Ryoji, Kutty, Shelby, Rozanski, George J., Ramanadham, Sasanka, Singh, Jaipaul, Bidasee, Keshore R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422706/
https://ncbi.nlm.nih.gov/pubmed/22648972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.078352
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