Gain of function of cardiac ryanodine receptor in a rat model of type 1 diabetes

AIMS: Ventricular myocytes isolated from hearts of streptozotocin (STZ)-diabetic rats exhibit increased spontaneous Ca(2+) release. Studies attribute this defect to an enhancement in activity of type 2 ryanodine receptor (RyR2). To date, underlying reasons for RyR2 dysregulation remain undefined. Th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tian, Chengju, Hong Shao, Chun, Moore, Caronda J., Kutty, Shelby, Walseth, Timothy, DeSouza, Cyrus, Bidasee, Keshore R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125072/
https://ncbi.nlm.nih.gov/pubmed/21421556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr076
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados