Gain of function of cardiac ryanodine receptor in a rat model of type 1 diabetes

AIMS: Ventricular myocytes isolated from hearts of streptozotocin (STZ)-diabetic rats exhibit increased spontaneous Ca(2+) release. Studies attribute this defect to an enhancement in activity of type 2 ryanodine receptor (RyR2). To date, underlying reasons for RyR2 dysregulation remain undefined. Th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tian, Chengju, Hong Shao, Chun, Moore, Caronda J., Kutty, Shelby, Walseth, Timothy, DeSouza, Cyrus, Bidasee, Keshore R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2011
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125072/
https://ncbi.nlm.nih.gov/pubmed/21421556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr076
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg