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CCDI: a new ligand that modulates mammalian type 1 ryanodine receptor (RyR1)
BACKGROUND AND PURPOSE: Ryanodine receptors (RyRs) are Ca(2+)-release channels on the sarco(endo)plasmic reticulum that modulate a wide array of physiological functions. Three RyR isoforms are present in cells: RyR1, RyR2 and RyR3. To date, there are no reports on ligands that modulate RyR in an iso...
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| Vydáno v: | Br J Pharmacol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BlackWell Publishing Ltd
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4243982/ https://ncbi.nlm.nih.gov/pubmed/24819467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12764 |
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