MALONDIALDEHYDE AND 4-HYDROXYNONENAL ADDUCTS ARE NOT FORMED ON CARDIAC RYANODINE RECEPTOR (RyR2) AND SARCO(ENDO)PLASMIC RETICULUM Ca(2+) ATPase (SERCA2) IN DIABETES

Recently, we reported an elevated level of glucose-derived carbonyl adducts on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA2) in hearts of streptozotocin(STZ)-induced diabetic rats. We also showed these adduct impaired RyR2 and SERCA2 activities, and altere...

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Udgivet i:Mol Cell Biochem
Main Authors: Moore, Caronda J., Shao, Chun Hong, Nagai, Ryoji, Kutty, Shelby, Singh, Jaipaul, Bidasee, Keshore R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720987/
https://ncbi.nlm.nih.gov/pubmed/23354458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-013-1558-1
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