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Genetic ablation of Adamts13 gene dramatically accelerates the formation of early atherosclerosis in a murine model

OBJECTIVE: ADAMTS13 cleaves von Willebrand factor (VWF), thereby modulating thrombosis and inflammation. Low plasma ADAMTS13 activity is associated with cardiovascular events including myocardial and cerebral infarction. Here, we investigated the role of ADAMTS13 in the development of early atherosc...

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Bibliografiska uppgifter
Huvudupphovsmän: Tohyama, Junichiro, Bauer, Robert C., Cao, Na Nora, Rader, Daniel J., Zheng, X. Long
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422623/
https://ncbi.nlm.nih.gov/pubmed/22652598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.247262
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