Knockout of Adamts7, A Novel CAD Locus in Humans, Reduces Atherosclerosis in Mice

BACKGROUND: Genome-wide association studies (GWAS) have established ADAMTS7 as a locus for coronary artery disease (CAD) in humans. Yet, these studies fail to provide directionality for the association between ADAMTS7 and CAD. Previous reports have implicated ADAMTS7 in the regulation of vascular sm...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Bauer, Robert C., Tohyama, Junichiro, Cui, Jian, Cheng, Lan, Yang, Jifu, Zhang, Xuan, Ou, Kristy, Paschos, Georgios K., Zheng, X. Long, Parmacek, Michael S., Rader, Daniel J., Reilly, Muredach P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382454/
https://ncbi.nlm.nih.gov/pubmed/25712206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.012669
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