Knockout of Adamts7, A Novel CAD Locus in Humans, Reduces Atherosclerosis in Mice

BACKGROUND: Genome-wide association studies (GWAS) have established ADAMTS7 as a locus for coronary artery disease (CAD) in humans. Yet, these studies fail to provide directionality for the association between ADAMTS7 and CAD. Previous reports have implicated ADAMTS7 in the regulation of vascular sm...

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Bibliographic Details
Published in:Circulation
Main Authors: Bauer, Robert C., Tohyama, Junichiro, Cui, Jian, Cheng, Lan, Yang, Jifu, Zhang, Xuan, Ou, Kristy, Paschos, Georgios K., Zheng, X. Long, Parmacek, Michael S., Rader, Daniel J., Reilly, Muredach P.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382454/
https://ncbi.nlm.nih.gov/pubmed/25712206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.012669
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