Role of Human UDP-Glucuronosyltransferases in the Biotransformation of the Triazoloacridinone and Imidazoacridinone Antitumor Agents C-1305 and C-1311: Highly Selective Substrates for UGT1A10

Lignende værker

• Metabolic Transformation of Antitumor Acridinone C-1305 but Not C-1311 via Selective Cellular Expression of UGT1A10 Increases Cytotoxic Response: Implications for Clinical Use
  af: Pawlowska, Monika, et al.
  Udgivet: (2013)
• The crystal structure of human UDP-glucuronosyltransferase 2B7 C-terminal end is the first mammalian UGT target to be revealed: the significance for human UGTs from both the 1A and 2B families
  af: Radominska-Pandya, Anna, et al.
  Udgivet: (2010)
• Electrochemical and in silico approaches for liver metabolic oxidation of antitumor-active triazoloacridinone C-1305()
  af: Potęga, Agnieszka, et al.
  Udgivet: (2020)
• Analysis of R- and S-Hydroxywarfarin Glucuronidation Catalyzed by Human Liver Microsomes and Recombinant UDP-Glucuronosyltransferases
  af: Bratton, Stacie M., et al.
  Udgivet: (2012)
• CYP3A4 overexpression enhances apoptosis induced by anticancer agent imidazoacridinone C-1311, but does not change the metabolism of C-1311 in CHO cells
  af: Pawłowska, Monika, et al.
  Udgivet: (2014)