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Multiple barriers in forced rupture of protein complexes

Curvatures in the most probable rupture force (f(*)) versus log-loading rate (log r(f)) observed in dynamic force spectroscopy (DFS) on biomolecular complexes are interpreted using a one-dimensional free energy profile with multiple barriers or a single barrier with force-dependent transition state....

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Detalhes bibliográficos
Main Authors: Hyeon, Changbong, Thirumalai, D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Institute of Physics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422331/
https://ncbi.nlm.nih.gov/pubmed/22894385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4739747
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