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Directly measuring single-molecule heterogeneity using force spectroscopy
One of the most intriguing results of single-molecule experiments on proteins and nucleic acids is the discovery of functional heterogeneity: the observation that complex cellular machines exhibit multiple, biologically active conformations. The structural differences between these conformations may...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941464/ https://ncbi.nlm.nih.gov/pubmed/27317744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518389113 |
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