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Compaction and Tensile Forces Determine the Accuracy of Folding Landscape Parameters from Single Molecule Pulling Experiments

We establish a framework for assessing whether the transition state location of a biopolymer, which can be inferred from single molecule pulling experiments, corresponds to the ensemble of structures that have equal probability of reaching either the folded or unfolded states (P(fold) = 0.5). Using...

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Detalhes bibliográficos
Main Authors: Morrison, Greg, Hyeon, Changbong, Hinczewski, Michael, Thirumalai, D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571105/
https://ncbi.nlm.nih.gov/pubmed/21517423
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