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Chain Length Determines the Folding Rates of RNA

We show that the folding rates (k(F)s) of RNA are determined by N, the number of nucleotides. By assuming that the distribution of free-energy barriers separating the folded and the unfolded states is Gaussian, which follows from central limit theorem arguments and polymer physics concepts, we show...

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Detalhes bibliográficos
Main Authors: Hyeon, Changbong, Thirumalai, D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274808/
https://ncbi.nlm.nih.gov/pubmed/22325296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.003
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