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Chain Length Determines the Folding Rates of RNA

We show that the folding rates (k(F)s) of RNA are determined by N, the number of nucleotides. By assuming that the distribution of free-energy barriers separating the folded and the unfolded states is Gaussian, which follows from central limit theorem arguments and polymer physics concepts, we show...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hyeon, Changbong, Thirumalai, D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274808/
https://ncbi.nlm.nih.gov/pubmed/22325296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.003
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