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Force-dependent hopping rates of RNA hairpins can be estimated from accurate measurement of the folding landscapes
The sequence-dependent folding landscapes of nucleic acid hairpins reflect much of the complexity of biomolecular folding. Folding trajectories, generated by using single-molecule force-clamp experiments by attaching semiflexible polymers to the ends of hairpins, have been used to infer their foldin...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2474478/ https://ncbi.nlm.nih.gov/pubmed/18621721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802484105 |
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