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Force-dependent hopping rates of RNA hairpins can be estimated from accurate measurement of the folding landscapes

The sequence-dependent folding landscapes of nucleic acid hairpins reflect much of the complexity of biomolecular folding. Folding trajectories, generated by using single-molecule force-clamp experiments by attaching semiflexible polymers to the ends of hairpins, have been used to infer their foldin...

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Autors principals: Hyeon, Changbong, Morrison, Greg, Thirumalai, D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474478/
https://ncbi.nlm.nih.gov/pubmed/18621721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802484105
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