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Can energy landscape roughness of proteins and RNA be measured by using mechanical unfolding experiments?
By considering temperature effects on the mechanical unfolding rates of proteins and RNA, whose energy landscape is rugged, the question posed in the title is answered in the affirmative. Adopting a theory by Zwanzig [Zwanzig, R. (1988) Proc. Natl. Acad. Sci. USA 85, 2029-2030], we show that, becaus...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193524/ https://ncbi.nlm.nih.gov/pubmed/12934020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1833310100 |
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