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Measurement of energy landscape roughness of folded and unfolded proteins

The dynamics of protein conformational changes, from protein folding to smaller changes, such as those involved in ligand binding, are governed by the properties of the conformational energy landscape. Different techniques have been used to follow the motion of a protein over this landscape and thus...

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Detalhes bibliográficos
Main Authors: Milanesi, Lilia, Waltho, Jonathan P., Hunter, Christopher A., Shaw, Daniel J., Beddard, Godfrey S., Reid, Gavin D., Dev, Sagarika, Volk, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511724/
https://ncbi.nlm.nih.gov/pubmed/23150572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211764109
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