Genetic Variation in the Plasmodium falciparum Circumsporozoite Protein in India and Its Relevance to RTS,S Malaria Vaccine

RTS,S is the most advanced malaria vaccine candidate, currently under phase-III clinical trials in Africa. This Plasmodium falciparum vaccine contains part of the central repeat region and the complete C-terminal T cell epitope region (Th2R and Th3R) of the circumsporozoite protein (CSP). Since natu...

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Autors principals: Zeeshan, Mohammad, Alam, Mohammad Tauqeer, Vinayak, Sumiti, Bora, Hema, Tyagi, Rupesh Kumar, Alam, Mohd Shoeb, Choudhary, Vandana, Mittra, Pooja, Lumb, Vanshika, Bharti, Praveen Kumar, Udhayakumar, Venkatachalam, Singh, Neeru, Jain, Vidhan, Singh, Pushpendra Pal, Sharma, Yagya Dutta
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422267/
https://ncbi.nlm.nih.gov/pubmed/22912873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043430
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