Genetic Variation in the Plasmodium falciparum Circumsporozoite Protein in India and Its Relevance to RTS,S Malaria Vaccine

RTS,S is the most advanced malaria vaccine candidate, currently under phase-III clinical trials in Africa. This Plasmodium falciparum vaccine contains part of the central repeat region and the complete C-terminal T cell epitope region (Th2R and Th3R) of the circumsporozoite protein (CSP). Since natu...

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Detalhes bibliográficos
Main Authors: Zeeshan, Mohammad, Alam, Mohammad Tauqeer, Vinayak, Sumiti, Bora, Hema, Tyagi, Rupesh Kumar, Alam, Mohd Shoeb, Choudhary, Vandana, Mittra, Pooja, Lumb, Vanshika, Bharti, Praveen Kumar, Udhayakumar, Venkatachalam, Singh, Neeru, Jain, Vidhan, Singh, Pushpendra Pal, Sharma, Yagya Dutta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422267/
https://ncbi.nlm.nih.gov/pubmed/22912873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043430
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