Extensive Genetic Diversity in the Plasmodium falciparum Na(+)/H(+) Exchanger 1 Transporter Protein Implicated in Quinine Resistance

The Plasmodium falciparum Na(+)/H(+) exchanger (Pfnhe-1) locus at chromosome 13 and another locus at chromosome 9 have recently been proposed to influence quinine resistance. Here, we sequenced the ms4760 locus of the Pfnhe-1 gene from 244 P. falciparum isolates collected from five different regions...

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Detalhes bibliográficos
Main Authors: Vinayak, Sumiti, Alam, Mohammad Tauqeer, Upadhyay, Mala, Das, Manoj K., Dev, Vas, Singh, Neeru, Dash, Aditya P., Sharma, Yagya D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167966/
https://ncbi.nlm.nih.gov/pubmed/17923493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00317-07
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