Sequence diversity and natural selection at domain I of the apical membrane antigen 1 among Indian Plasmodium falciparum populations

BACKGROUND: The Plasmodium falciparum apical membrane antigen 1 (AMA1) is a leading malaria vaccine candidate antigen. The complete AMA1 protein is comprised of three domains where domain I exhibits high sequence polymorphism and is thus named as the hyper-variable region (HVR). The present study de...

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Detalhes bibliográficos
Main Authors: Garg, Sheena, Alam, Mohammad T, Das, Manoj K, Dev, Vas, Kumar, Ashwani, Dash, Aditya P, Sharma, Yagya D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211494/
https://ncbi.nlm.nih.gov/pubmed/18031585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-6-154
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