A Novel Highly Potent Therapeutic Antibody Neutralizes Multiple Human Chemokines and Mimics Viral Immune Modulation

Chemokines play a key role in leukocyte recruitment during inflammation and are implicated in the pathogenesis of a number of autoimmune diseases. As such, inhibiting chemokine signaling has been of keen interest for the development of therapeutic agents. This endeavor, however, has been hampered du...

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Detalhes bibliográficos
Main Authors: Scalley-Kim, Michelle L., Hess, Bruce W., Kelly, Ryan L., Krostag, Anne-Rachel F., Lustig, Kurt H., Marken, John S., Ovendale, Pamela J., Posey, Aaron R., Smolak, Pamela J., Taylor, Janelle D. L., Wood, C. L., Bienvenue, David L., Probst, Peter, Salmon, Ruth A., Allison, Daniel S., Foy, Teresa M., Raport, Carol J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422223/
https://ncbi.nlm.nih.gov/pubmed/22912856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043332
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