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Combination Treatment with HER-2 and VEGF Peptide Mimics Induces Potent Anti-tumor and Anti-angiogenic Responses in Vitro and in Vivo

HER-2 is a member of the EGF receptor family and is overexpressed in 20–30% of breast cancers. HER-2 overexpression causes increased expression of VEGF at both the RNA and protein levels. HER-2 and VEGF are therefore considered good targets for cancer treatment, which has led to the development of t...

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Detalhes bibliográficos
Main Authors: Foy, Kevin C., Liu, Zhenzhen, Phillips, Gary, Miller, Megan, Kaumaya, Pravin T. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075707/
https://ncbi.nlm.nih.gov/pubmed/21325276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.216820
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