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Engineered Conformation-dependent VEGF Peptide Mimics Are Effective in Inhibiting VEGF Signaling Pathways

Angiogenesis, or formation of new blood vessels, is crucial to cancer tumor growth. Tumor growth, progression, and metastasis are critically influenced by the production of the pro-angiogenic vascular endothelial growth factor (VEGF). Promising anti-angiogenic drugs are currently available; however,...

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Sonraí Bibleagrafaíochta
Main Authors: Vicari, Daniele, Foy, Kevin C., Liotta, Eric M., Kaumaya, Pravin T. P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075706/
https://ncbi.nlm.nih.gov/pubmed/21321115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.216812
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