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Soluble mimics of a chemokine receptor: Chemokine binding by receptor elements juxtaposed on a soluble scaffold

Despite the broad biological importance of G protein–coupled receptors (GPCRs), ligand recognition by GPCRs remains poorly understood. To explore the roles of GPCR extracellular elements in ligand binding and to provide a tractable system for structural analyses of GPCR/ligand interactions, we have...

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Autors principals: Datta, Amita, Stone, Martin J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366953/
https://ncbi.nlm.nih.gov/pubmed/14573861
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