Response of Simian Immunodeficiency Virus to the Novel Nucleoside Reverse Transcriptase Inhibitor 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine In Vitro and In Vivo

Eitemau Tebyg

• Oral Administration of the Nucleoside EFdA (4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine) Provides Rapid Suppression of HIV Viremia in Humanized Mice and Favorable Pharmacokinetic Properties in Mice and the Rhesus Macaque
  gan: Stoddart, Cheryl A., et al.
  Cyhoeddwyd: (2015)
• Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs
  gan: Hachiya, Atsuko, et al.
  Cyhoeddwyd: (2013)
• Mechanism of Interaction of Human Mitochondrial DNA Polymerase γ with the Novel Nucleoside Reverse Transcriptase Inhibitor 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine Indicates a Low Potential for Host Toxicity
  gan: Sohl, Christal D., et al.
  Cyhoeddwyd: (2012)
• Effects of Substitutions at the 4′ and 2 Positions on the Bioactivity of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine
  gan: Kirby, Karen A., et al.
  Cyhoeddwyd: (2013)
• THE SUGAR RING CONFORMATION OF 4’-ETHYNYL-2-FLUORO-2’-DEOXYADENOSINE AND ITS RECOGNITION BY THE POLYMERASE ACTIVE SITE OF HIV REVERSE TRANSCRIPTASE
  gan: Kirby, K.A., et al.
  Cyhoeddwyd: (2011)