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Response of Simian Immunodeficiency Virus to the Novel Nucleoside Reverse Transcriptase Inhibitor 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine In Vitro and In Vivo

Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) are essential components in first-line therapy for human immunodeficiency virus (HIV) infection. However, long-term treatment with existing NRTIs can be associated with significant toxic side effects and the emergence of drug-resistant s...

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Bibliografiske detaljer
Main Authors: Murphey-Corb, Michael, Rajakumar, Premeela, Michael, Heather, Nyaundi, Julia, Didier, Peter J., Reeve, Aaron B., Mitsuya, Hiroaki, Sarafianos, Stefan G., Parniak, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421895/
https://ncbi.nlm.nih.gov/pubmed/22713337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00723-12
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