Identification of (+)-Erythro-Mefloquine as an Active Enantiomer with Greater Efficacy than Mefloquine against Mycobacterium avium Infection in Mice

Infection caused by Mycobacterium avium is common in AIDS patients who do not receive treatment with highly active antiretroviral therapy (HAART) or who develop resistance to anti-HIV therapy. Mefloquine, a racemic mixture used for malaria prophylaxis and treatment, is bactericidal against M. avium...

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Detaylı Bibliyografya
Asıl Yazarlar: Bermudez, Luiz E., Inderlied, Clark B., Kolonoski, Peter, Chee, Christopher B., Aralar, Priscilla, Petrofsky, Mary, Parman, Toufan, Green, Carol E., Lewin, Anita H., Ellis, William Y., Young, Lowell S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2012
Konular:
Experimental Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421598/
https://ncbi.nlm.nih.gov/pubmed/22615290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00320-12
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