Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation

Cofactors for estrogen receptor α (ERα) can modulate gene activity by posttranslationally modifying histone tails at target promoters. Here, we found that stimulation of ERα-positive cells with 17β-estradiol (E2) promotes global citrullination of histone H3 arginine 26 (H3R26) on chromatin. Addition...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Zhang, Xuesen, Bolt, Michael, Guertin, Michael J., Chen, Wei, Zhang, Sheng, Cherrington, Brian D., Slade, Daniel J., Dreyton, Christina J., Subramanian, Venkataraman, Bicker, Kevin L., Thompson, Paul R., Mancini, Michael A., Lis, John T., Coonrod, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421185/
https://ncbi.nlm.nih.gov/pubmed/22853951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203280109
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares