Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development

Peptidylarginine deiminase (PADI) enzymes are increasingly being associated with the regulation of chromatin structure and gene activity via histone citrullination. As one of the PADI family members, PADI1 has been mainly reported to be expressed in the epidermis and uterus, where the protein in ker...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Xiaoqian, Liu, Xiaoqiu, Zhang, Mei, Li, Tingting, Muth, Aaron, Thompson, Paul R., Coonrod, Scott A., Zhang, Xuesen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5144008/
https://ncbi.nlm.nih.gov/pubmed/27929094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38727
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