Potential Role of Peptidylarginine Deiminase Enzymes and Protein Citrullination in Cancer Pathogenesis

The peptidylarginine deiminases (PADs) are a family of posttranslational modification enzymes that catalyze the conversion of positively charged protein-bound arginine and methylarginine residues to the uncharged, nonstandard amino acid citrulline. This enzymatic activity is referred to as citrullin...

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Bibliographic Details
Main Authors: Mohanan, Sunish, Cherrington, Brian D., Horibata, Sachi, McElwee, John L., Thompson, Paul R., Coonrod, Scott A.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457611/
https://ncbi.nlm.nih.gov/pubmed/23019525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/895343
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