TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. We previously showed that the pivotal effector of this pathway, YAP, is amplified in tumors and promotes epithelial-to-mesenchymal transition (EMT) and mal...

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Autori principali: Yang, Nuo, Morrison, Carl D., Liu, Peijun, Miecznikowski, Jeff, Bshara, Wiam, Han, Suxia, Zhu, Qing, Omilian, Angela R., Li, Xu, Zhang, Jianmin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419062/
https://ncbi.nlm.nih.gov/pubmed/22825057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21386
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