TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. We previously showed that the pivotal effector of this pathway, YAP, is amplified in tumors and promotes epithelial-to-mesenchymal transition (EMT) and mal...

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Detalhes bibliográficos
Main Authors: Yang, Nuo, Morrison, Carl D., Liu, Peijun, Miecznikowski, Jeff, Bshara, Wiam, Han, Suxia, Zhu, Qing, Omilian, Angela R., Li, Xu, Zhang, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419062/
https://ncbi.nlm.nih.gov/pubmed/22825057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21386
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