TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. We previously showed that the pivotal effector of this pathway, YAP, is amplified in tumors and promotes epithelial-to-mesenchymal transition (EMT) and mal...

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Détails bibliographiques
Auteurs principaux: Yang, Nuo, Morrison, Carl D., Liu, Peijun, Miecznikowski, Jeff, Bshara, Wiam, Han, Suxia, Zhu, Qing, Omilian, Angela R., Li, Xu, Zhang, Jianmin
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
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Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419062/
https://ncbi.nlm.nih.gov/pubmed/22825057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21386
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