TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. We previously showed that the pivotal effector of this pathway, YAP, is amplified in tumors and promotes epithelial-to-mesenchymal transition (EMT) and mal...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Yang, Nuo, Morrison, Carl D., Liu, Peijun, Miecznikowski, Jeff, Bshara, Wiam, Han, Suxia, Zhu, Qing, Omilian, Angela R., Li, Xu, Zhang, Jianmin
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2012
Предметы:
Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419062/
https://ncbi.nlm.nih.gov/pubmed/22825057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21386
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы