Overexpression of YAP and TAZ Is an Independent Predictor of Prognosis in Colorectal Cancer and Related to the Proliferation and Metastasis of Colon Cancer Cells

BACKGROUND AND OBJECTIVE: Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are nuclear effectors of the Hippo pathway. Although they are abundantly expressed in the cytoplasm and nuclei of human colorectal cancer (CRC), and related to tumor proliferation sta...

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Bibliographic Details
Main Authors: Wang, Lijuan, Shi, Shengjia, Guo, Zhangyan, Zhang, Xiang, Han, Suxia, Yang, Angang, Wen, Weihong, Zhu, Qing
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677905/
https://ncbi.nlm.nih.gov/pubmed/23762387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065539
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