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Overexpression of YAP and TAZ Is an Independent Predictor of Prognosis in Colorectal Cancer and Related to the Proliferation and Metastasis of Colon Cancer Cells

BACKGROUND AND OBJECTIVE: Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are nuclear effectors of the Hippo pathway. Although they are abundantly expressed in the cytoplasm and nuclei of human colorectal cancer (CRC), and related to tumor proliferation sta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Lijuan, Shi, Shengjia, Guo, Zhangyan, Zhang, Xiang, Han, Suxia, Yang, Angang, Wen, Weihong, Zhu, Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3677905/
https://ncbi.nlm.nih.gov/pubmed/23762387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065539
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