TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin

The Hippo signaling pathway regulates cellular proliferation and survival, thus exerting profound effects on normal cell fate and tumorigenesis. We previously showed that the pivotal effector of this pathway, YAP, is amplified in tumors and promotes epithelial-to-mesenchymal transition (EMT) and mal...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yang, Nuo, Morrison, Carl D., Liu, Peijun, Miecznikowski, Jeff, Bshara, Wiam, Han, Suxia, Zhu, Qing, Omilian, Angela R., Li, Xu, Zhang, Jianmin
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419062/
https://ncbi.nlm.nih.gov/pubmed/22825057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21386
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky