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USP1 Regulates TAZ Protein Stability Through Ubiquitin Modifications in Breast Cancer

SIMPLE SUMMARY: Triple-Negative breast cancer (TNBC) is the most aggressive form of breast cancer in women. Targeted therapies for the treatment of this disease are severely lacking. Through mechanistic studies of the key component of Hippo signaling pathway, Transcriptional co-activator with PDZ-bi...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Mussell, Ashley, Shen, He, Chen, Yanmin, Mastri, Michalis, Eng, Kevin H., Bshara, Wiam, Frangou, Costa, Zhang, Jianmin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690829/
https://ncbi.nlm.nih.gov/pubmed/33114077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113090
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