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USP1 Regulates TAZ Protein Stability Through Ubiquitin Modifications in Breast Cancer

SIMPLE SUMMARY: Triple-Negative breast cancer (TNBC) is the most aggressive form of breast cancer in women. Targeted therapies for the treatment of this disease are severely lacking. Through mechanistic studies of the key component of Hippo signaling pathway, Transcriptional co-activator with PDZ-bi...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Mussell, Ashley, Shen, He, Chen, Yanmin, Mastri, Michalis, Eng, Kevin H., Bshara, Wiam, Frangou, Costa, Zhang, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690829/
https://ncbi.nlm.nih.gov/pubmed/33114077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113090
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