Identification of TAZ-Dependent Breast Cancer Vulnerabilities Using a Chemical Genomics Screening Approach

Breast cancer stem cells (BCSCs) represent a subpopulation of tumor cells that can self-renew and generate tumor heterogeneity. Targeting BCSCs may ameliorate therapy resistance, tumor growth, and metastatic progression. However, the origin and molecular mechanisms underlying their cellular properti...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Shen, He, Chen, Yanmin, Wan, Yin, Liu, Tao, Wang, Jianmin, Zhang, Yali, Wei, Lei, Hu, Qiang, Xu, Bo, Chernov, Mikhail, Frangou, Costa, Zhang, Jianmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239392/
https://ncbi.nlm.nih.gov/pubmed/34211974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.673374
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