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Targeting TAZ-driven Human Breast Cancer by Inhibiting a SKP2-p27 Signaling Axis

Deregulated expression of the transcriptional co-activator with PDZ-binding motif (WWTR1/TAZ) is a common feature of basal-like breast cancer (BLBC). Yet, how oncogenic TAZ regulates cell cycle progression and proliferation in breast cancer remains poorly understood, and whether TAZ is required for...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Shen, He, Yang, Nuo, Truskinovsky, Alexander, Chen, Yanmin, Mussell, Ashley L., Nowak, Norma J., Kobzik, Lester, Frangou, Costa, Zhang, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318031/
https://ncbi.nlm.nih.gov/pubmed/30237296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0332
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