Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets

Triple-negative breast cancer (TNBC) accounts for approximately 15–20% of all breast cancer (BC) cases and contributes disproportionately to BC mortality. TAZ, a key transducer of the Hippo pathway, has recently been demonstrated to confer breast cancer stem cell (CSC) traits. However, TAZ target ge...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Frangou, Costa, Li, Ying-Wei, Shen, He, Yang, Nuo, Wilson, Kayla E., Blijlevens, Maxime, Guo, Jin, Nowak, Norma J., Zhang, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323005/
https://ncbi.nlm.nih.gov/pubmed/25361000
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