DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

To migrate efficiently through the interstitium, dendritic cells (DCs) constantly adapt their shape to the given structure of the extracellular matrix and follow the path of least resistance. It is known that this amoeboid migration of DCs requires Cdc42, yet the upstream regulators critical for loc...

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Autors principals: Harada, Yosuke, Tanaka, Yoshihiko, Terasawa, Masao, Pieczyk, Markus, Habiro, Katsuyoshi, Katakai, Tomoya, Hanawa-Suetsugu, Kyoko, Kukimoto-Niino, Mutsuko, Nishizaki, Tomoko, Shirouzu, Mikako, Duan, Xuefeng, Uruno, Takehito, Nishikimi, Akihiko, Sanematsu, Fumiyuki, Yokoyama, Shigeyuki, Stein, Jens V., Kinashi, Tatsuo, Fukui, Yoshinori
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418773/
https://ncbi.nlm.nih.gov/pubmed/22461490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-407098
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