Broad segmental progeroid changes in short-lived Ercc1(−/Δ7) mice

Genome maintenance is considered a prime longevity assurance mechanism as apparent from many progeroid human syndromes that are caused by genome maintenance defects. The ERCC1 protein is involved in three genome maintenance systems: nucleotide excision repair, interstrand cross-link repair, and homo...

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Detalhes bibliográficos
Main Authors: Dollé, Martijn E.T., Kuiper, Raoul V., Roodbergen, Marianne, Robinson, Joke, de Vlugt, Sisca, Wijnhoven, Susan W.P., Beems, Rudolf B., de la Fonteyne, Liset, de With, Piet, van der Pluijm, Ingrid, Niedernhofer, Laura J., Hasty, Paul, Vijg, Jan, Hoeijmakers, Jan H.J., van Steeg, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: Co-Action Publishing 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417667/
https://ncbi.nlm.nih.gov/pubmed/22953029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/pba.v1i0.7219
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