Drug Experience Epigenetically Primes Fosb Gene Inducibility in Rat Nucleus Accumbens

ΔFosB, a Fosb gene product, is induced in nucleus accumbens (NAc) and caudate–putamen (CPu) by repeated exposure to drugs of abuse such as cocaine. This induction contributes to aberrant patterns of gene expression and behavioral abnormalities seen with repeated drug exposure. Here, we assessed whet...

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Autors principals: Damez-Werno, Diane, LaPlant, Quincey, Sun, HaoSheng, Scobie, Kimberly N., Dietz, David M., Walker, Ian M., Koo, Ja Wook, Vialou, Vincent F., Mouzon, Ezekiell, Russo, Scott J., Nestler, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417057/
https://ncbi.nlm.nih.gov/pubmed/22836260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1290-12.2012
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