Drug Experience Epigenetically Primes Fosb Gene Inducibility in Rat Nucleus Accumbens

ΔFosB, a Fosb gene product, is induced in nucleus accumbens (NAc) and caudate–putamen (CPu) by repeated exposure to drugs of abuse such as cocaine. This induction contributes to aberrant patterns of gene expression and behavioral abnormalities seen with repeated drug exposure. Here, we assessed whet...

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Hlavní autoři: Damez-Werno, Diane, LaPlant, Quincey, Sun, HaoSheng, Scobie, Kimberly N., Dietz, David M., Walker, Ian M., Koo, Ja Wook, Vialou, Vincent F., Mouzon, Ezekiell, Russo, Scott J., Nestler, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
Témata:
Brief Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417057/
https://ncbi.nlm.nih.gov/pubmed/22836260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1290-12.2012
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