Drug Experience Epigenetically Primes Fosb Gene Inducibility in Rat Nucleus Accumbens

ΔFosB, a Fosb gene product, is induced in nucleus accumbens (NAc) and caudate–putamen (CPu) by repeated exposure to drugs of abuse such as cocaine. This induction contributes to aberrant patterns of gene expression and behavioral abnormalities seen with repeated drug exposure. Here, we assessed whet...

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Bibliografiske detaljer
Main Authors: Damez-Werno, Diane, LaPlant, Quincey, Sun, HaoSheng, Scobie, Kimberly N., Dietz, David M., Walker, Ian M., Koo, Ja Wook, Vialou, Vincent F., Mouzon, Ezekiell, Russo, Scott J., Nestler, Eric J.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
Fag:
Brief Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417057/
https://ncbi.nlm.nih.gov/pubmed/22836260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1290-12.2012
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