Drug Experience Epigenetically Primes Fosb Gene Inducibility in Rat Nucleus Accumbens

ΔFosB, a Fosb gene product, is induced in nucleus accumbens (NAc) and caudate–putamen (CPu) by repeated exposure to drugs of abuse such as cocaine. This induction contributes to aberrant patterns of gene expression and behavioral abnormalities seen with repeated drug exposure. Here, we assessed whet...

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Detalhes bibliográficos
Main Authors: Damez-Werno, Diane, LaPlant, Quincey, Sun, HaoSheng, Scobie, Kimberly N., Dietz, David M., Walker, Ian M., Koo, Ja Wook, Vialou, Vincent F., Mouzon, Ezekiell, Russo, Scott J., Nestler, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417057/
https://ncbi.nlm.nih.gov/pubmed/22836260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1290-12.2012
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