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A Resolution of the Mutation Load Paradox in Humans

Current information on the rate of mutation and the fraction of sites in the genome that are subject to selection suggests that each human has received, on average, at least two new harmful mutations from its parents. These mutations were subsequently removed by natural selection through reduced sur...

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書誌詳細
主要な著者: Lesecque, Yann, Keightley, Peter D., Eyre-Walker, Adam
フォーマット: Artigo
言語:Inglês
出版事項: Genetics Society of America 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416010/
https://ncbi.nlm.nih.gov/pubmed/22661324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.140343
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