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How Much of the Variation in the Mutation Rate Along the Human Genome Can Be Explained?

It has been claimed recently that it may be possible to predict the rate of de novo mutation of each site in the human genome with a high degree of accuracy [Michaelson et al. (2012), Cell 151: 1431−1442]. We show that this claim is unwarranted. By considering the correlation between the rate of de...

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Hlavní autoři: Eyre-Walker, Adam, Eyre-Walker, Ying Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169158/
https://ncbi.nlm.nih.gov/pubmed/24996580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.012849
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