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A Resolution of the Mutation Load Paradox in Humans
Current information on the rate of mutation and the fraction of sites in the genome that are subject to selection suggests that each human has received, on average, at least two new harmful mutations from its parents. These mutations were subsequently removed by natural selection through reduced sur...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3416010/ https://ncbi.nlm.nih.gov/pubmed/22661324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.140343 |
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