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A Resolution of the Mutation Load Paradox in Humans

Current information on the rate of mutation and the fraction of sites in the genome that are subject to selection suggests that each human has received, on average, at least two new harmful mutations from its parents. These mutations were subsequently removed by natural selection through reduced sur...

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Bibliografische gegevens
Hoofdauteurs: Lesecque, Yann, Keightley, Peter D., Eyre-Walker, Adam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416010/
https://ncbi.nlm.nih.gov/pubmed/22661324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.140343
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