Development of ‘DFG-out’ inhibitors of gatekeeper mutant kinases

Ítems similars

• Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRα, Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants
  per: Weisberg, Ellen, et al.
  Publicat: (2010)
• A Type-II Kinase Inhibitor Capable of Inhibiting the T315I “Gatekeeper” mutant of Bcr-Abl
  per: Choi, Hwan Geun, et al.
  Publicat: (2010)
• Discovery and Characterization of Novel Mutant FLT3 Kinase Inhibitors
  per: Weisberg, Ellen, et al.
  Publicat: (2010)
• Structural Elucidation of the DFG-Asp in and DFG-Asp out States of TAM Kinases and Insight into the Selectivity of Their Inhibitors
  per: Abdellah Messoussi, et al.
  Publicat: (2014-10-01)
• Structural Elucidation of the DFG-Asp in and DFG-Asp out States of TAM Kinases and Insight into the Selectivity of Their Inhibitors
  per: Messoussi, Abdellah, et al.
  Publicat: (2014)